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Founding Team
Dr. Michael Colicos
Ph.D., Montreal Neurological Institute, McGill University
Assistant Professor, Hotchkiss Brain Institute, University of Calgary
Newly established at the University of Calgary, my lab studies
the mechanisms of learning and memory both on a synaptic and on a systems level.
By studying living networks of cultured mammalian neurons, we can observe
individual synapses as they transmit their information. My lab is currently
developing a device call the NeuroSilicon interface, which is a way to
communicate with living neuronal cultures grown on a silicon wafer. This
technology was used to demonstrate that specific patterns of activity can cause
new synapse formation, a process believed to be fundamental to learning in the
brain. Currently we are using the NeuroSilicon interface to determine the role
of the synaptic cell adhesion molecule neuroligin in the process of synaptic
transmission and synaptic plasticity. Mutations in the neuroligin protein have
been linked to autism, and we are investigating how these mutations could cause
a change in synaptic function that leads to the condition.
Dr. Colin Dalton
Ph.D. (Biotechnology), University of Wales
Facility Manager, Advanced Micro/nanosystems Integration Facility (AMIF),
University of Calgary
Prior to emigrating to Canada from the UK 5 years ago, I worked for the
UK Lab-On-A-Chip Consortium and for a local start up company, primarily involved
with mass production commercialization of micro/nano products developed from
University research. Since coming to Canada I have been involved with setting up
the Advanced Micro/Nanosystems Integration Facility (AMIF) at the University of
Calgary. I also teach two graduate courses on Micro-Nano Systems Technologies
(MNT). At Neurosilicon, I aid in the commercialization of our products and
develop new technologies based on my MNT fabrication knowledge. My research
interests include dielectrophoresis, microfluidics, hybrid MNT devices and
Lab-On-A-Chip systems.
Dr. Lee Hartley
Ph.D., P.Eng.
Adjunct Professor, Electrical and Computer Engineering, University of Calgary
Director of Hardware Engineering, Advanced Bionics Corporation, Valencia,
California
My interests lie in hybrid microsystem
integration technologies targetting implantable devices and laboratory
diagnostic tools. Some specific areas of concentration include analog and mixed
signal integrated circuit design, optical microfluidic devices, speech signal
processing, embedded systems, neurostimulation strategies and hermetic
electromechanical packaging for implantable and wearable systems.
Dr. Graham Jullien
FIEEE, Ph.D., P.Eng.
iCORE Research Chair in Advanced Technology Information Processing
Systems (ATIPS), University of Calgary
My long-term interests have been in the general area of VLSI
Circuits and Systems for high performance digital signal processors at the
System-on-Chip (SOC) integration level. I have a specific interest in DSP and
crypto computations, particularly associated with the representation and
manipulation of numbers to perform the arithmetic. My interests also include the
implementation of Neural Networks (both artificial and cellular); low power and
low noise circuits for mixed-signal applications; new DSP algorithms; machine
vision systems; video and image processing; DSP systems for hearing instruments;
and recently, Micro Electro-Mechanical Systems (MEMs) and Quantum Cellular
Automata (QCA). The ATIPS Laboratory has recently developed links with several
groups in bio-engineering and medicine, and I am involved with several
interdisciplinary projects including bio-analysis using dielectrophoresis and a
low-power SoC bio-platform. These projects deal with the microsystem integration
of sophisticated integrated circuits, and MEMS/Microfluidic devices. The work on
QCA involves the development of a CAD tool that uses advanced simulation
techniques, at the quantum mechanical level, to provide a platform for
experimenting with this future technology.
Dr. Steven Munevar
Ph.D. - Biomedical Sciences, University of Massachusetts Medical School
M.B.A. - Worcester Polytechnic Institute
Business Development and Operations Management - Neurosilicon
Managing Director - Munevar & Associates, Life Science Technology Development
and Commercialization Company
As a Biomedical research scientist, my research interest was focused on applying
my diverse background in bioengineering and biomedical science towards
challenging life science related questions. Utilizing technology focused
strategies and tools, I have worked to address fundamental questions in life
science research areas such as cell and tissue mechanics, migration, signaling,
and regulation.
Seeking to play a greater role in the translation of life science research, I
set out to apply my engineering, life science, as well as business management
background towards bridging the gap between research bench and patient bedside
through the development and commercialization of life science related
technologies and innovations.
Currently, I play a role in the business development and operations management
at Neurosilicon. In this capacity, I apply my background and experience towards
advancing the successful development and commercialization of Neurosilicon’s
novel research technology and applications.
As part of the Neurosilicon team, it is my goal to continue to support and
advance the present and future goals of the company toward realizing
neuroscience related solutions that address the significant unmet need in this
area.
Dr. Naweed Syed
Ph.D. (Neurophysiology),
University of
Leeds
Professor and the Head of Department of Cell Biology & Anatomy, Faculty of
Medicine, University of Calgary
My prime interest is in the cellular and molecular basis of
rhythm generation and specific synapse formation. I specifically study the
intrinsic and network properties of various neuronal ensembles which underlie
rhythmic behaviors between the identified Lymnaea neurons such as locomotion and
respiration. I am also interested in investigating the cellular and molecular
mechanisms underlying nervous system development and plasticity. My research
program is directed towards determining how neurons find their path en route
towards their targets and form specific synaptic connections with other neurons,
and how their morphology and physiology is modified by injury or environmental
stress. Finding answers to these questions is fundamental if we are to fully
understand nervous system functions.
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